Explaining the Structure of Mitochondria

Tuesday, May 5, 2009 ·


Let’s have a look at the structure of mitochondria.

Inner membrane shows folded structure, forms invaginations into the mitochondrial cavity to increase the surface area for cellular respiration. These invaginations are called cristae which can be branched or unbranched. Cristae are the sites for ATP synthesis. Inner membrane is permeable only to oxygen, carbon dioxide, and water etc. About 1/5 of the total protein in a mitochondrion is present here.

Inter Cellular Space is the space between outer and inner membrane play important role in oxidative phosphorylation. Due to the permeablility of outer membrane it is rich in protein especially cytochrome C and other small molecules.

Matrix is the fluid or substance fill the mitochondrial cavity inside the inner membrane. It is rich in ribosomes, DNA, proteins and manganese. Ribosomes (of 70S type) present here are different from cytoplasmic ribosomes. Its DNA is of circular shape called mitochondrial DNA. About 2/3 of the total protein of mitochondrion is present in matrix. The matrix contains highly-concentrated mixture of enzymes. Enzymes for Kreb s cycle are also present here. The matrix play important role in ATP synthesis with the help of the ATP synthase present in inner membrane.

Oxysomes are knobs like structures present on the outer surface of outer membrane and on the inner surface on inner membrane. Oxysomes present on outer side are stalkless while those attached to inner surface have small stalk for attachment, this stalk is called F0 particles and rounded part is called F1 particle. Both have enzyme ATP-ase and are related to ATP synthesis. These are proteinaceous in nature. Oxysomes act as electron carrier and oxygen released results in the formation of water and ATP molecule.

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